Anti-Phospho-PDGFRA-Y849 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-Phospho-PDGFRA-Y849 Polyclonal Antibody

品牌:solarbio | 货号:K006241P

英文名称 Anti-Phospho-PDGFRA-Y849 Polyclonal Antibody
宿主 Rabbit
别名 CD140A;PDGFR-2;PDGFR2
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human
蛋白分子量 123kDa
Gene ID 5156
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A phospho specific peptide corresponding to residues surrounding Y849 of human PDGFRA
性状 液体
Public Immunogen Range A phospho specific peptide corresponding to residues surrounding Y849 of human PDGFRA
Subcellular Locations Cell membrane Single-pass type I membrane protein
Swiss Prot P16234
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.