Anti-SOCS6 Polyclonal Antibody
品牌:solarbio | 货号:K006128P
英文名称 |
Anti-SOCS6 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CIS-4;CIS4;HSPC060;SOCS-4;SOCS-6;SOCS4;SSI4;STAI4;STATI4 |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse |
蛋白分子量 |
60kDa |
Gene ID |
9306 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human SOCS6 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human SOCS6 |
Subcellular Locations |
Cytosol Plasma Membrane |
Swiss Prot |
O14544 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines. |