Anti-CSE1L Polyclonal Antibody
品牌:solarbio | 货号:K006036P
英文名称 |
Anti-CSE1L Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CAS;CSE1;XPO2 |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human |
蛋白分子量 |
110kDa |
Gene ID |
1434 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human CSE1L |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human CSE1L |
Subcellular Locations |
Cytoplasm Nucleus |
Swiss Prot |
P55060 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. |