Anti-PHLPP1 Polyclonal Antibody
品牌:solarbio | 货号:K006039P
| 英文名称 | Anti-PHLPP1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PHLPP;PLEKHE1;PPM3A;SCOP |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 185kDa |
| Gene ID | 23239 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PHLPP1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PHLPP1 |
| Subcellular Locations | Cell membrane Cytoplasm Membrane Nucleus Peripheral membrane protein |
| Swiss Prot | O60346 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling. |