Anti-CFD Polyclonal Antibody
品牌：solarbio | 货号：K005667P
| 英文名称 | Anti-CFD Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ADIPSIN;ADN;DF;PFD |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 27kDa |
| Gene ID | 1675 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CFD |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CFD |
| Subcellular Locations | Secreted |
| Swiss Prot | P00746 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease. |