Anti-NDUFV1 Polyclonal Antibody
品牌：solarbio | 货号：K005622P
| 英文名称 | Anti-NDUFV1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CI-51K;CI51KD;UQOR1 |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 51kDa |
| Gene ID | 4723 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human NDUFV1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human NDUFV1 |
| Subcellular Locations | Mitochondrion |
| Swiss Prot | P49821 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson’s disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |