Anti-NCALD Polyclonal Antibody
品牌:solarbio | 货号:K005613P
| 英文名称 | Anti-NCALD Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | NCALD |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 22kDa |
| Gene ID | 83988 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human NCALD |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human NCALD |
| Subcellular Locations | Cytosol Golgi apparatus |
| Swiss Prot | P61601 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined. |