Anti-NCALD Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-NCALD Polyclonal Antibody

品牌:solarbio | 货号:K005613P

英文名称 Anti-NCALD Polyclonal Antibody
宿主 Rabbit
别名 NCALD
应用 WB IHC IF
稀释比例 WB 1:500-2000. IHC 1:50-200. IF 1:50-100.
交叉反应 Human Mouse Rat
蛋白分子量 22kDa
Gene ID 83988
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human NCALD
性状 液体
Public Immunogen Range Recombinant protein of human NCALD
Subcellular Locations Cytosol Golgi apparatus
Swiss Prot P61601
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined.