Anti-NCALD Polyclonal Antibody
品牌:solarbio | 货号:K005613P
英文名称 |
Anti-NCALD Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
NCALD |
应用 |
WB IHC IF |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. IF 1:50-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
22kDa |
Gene ID |
83988 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human NCALD |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human NCALD |
Subcellular Locations |
Cytosol Golgi apparatus |
Swiss Prot |
P61601 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined. |