Anti-PLOD1 Polyclonal Antibody
品牌:solarbio | 货号:K005553P
英文名称 |
Anti-PLOD1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
EDS6;LH;LH1;LLH;PLOD |
应用 |
WB IF |
稀释比例 |
WB 1:500-2000. IF 1:50-200. |
交叉反应 |
Human Mouse |
蛋白分子量 |
84kDa |
Gene ID |
5351 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human PLOD1 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human PLOD1 |
Subcellular Locations |
Lumenal side Peripheral membrane protein Rough endoplasmic reticulum membrane |
Swiss Prot |
Q02809 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene. |