Anti-IL5 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-IL5 Polyclonal Antibody

品牌:solarbio | 货号:K005391P

英文名称 Anti-IL5 Polyclonal Antibody
宿主 Rabbit
别名 EDF;IL-5;TRF
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-100.
交叉反应 Human Mouse Rat
蛋白分子量 15kDa
Gene ID 3567
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human IL5
性状 液体
Public Immunogen Range Recombinant protein of human IL5
Subcellular Locations Secreted
Swiss Prot P05113
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.