Anti-CD8B Polyclonal Antibody
品牌：solarbio | 货号：K003646P
| 英文名称 | Anti-CD8B Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CD8B1;LEU2;LY3;LYT3;P37 |
| 应用 | WB |
| 稀释比例 | WB 1:200-500. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 24kDa |
| Gene ID | 926 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CD8B |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CD8B |
| Subcellular Locations | Cell membrane Secreted Single-pass type I membrane protein Single-pass type I membrane protein |
| Swiss Prot | P10966 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. |