Anti-OAS1 Polyclonal Antibody
品牌：solarbio | 货号：K003395P
| 英文名称 | Anti-OAS1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | E18/E16;IFI-4;OIAS;OIASI |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:50-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 46kDa |
| Gene ID | 4938 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human OAS1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human OAS1 |
| Subcellular Locations | Cytoplasm Endoplasmic reticulum Microsome Mitochondrion Nucleus Secreted |
| Swiss Prot | P00973 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene is induced by interferons and encodes a protein that synthesizes 2′,5′-oligoadenylates (2-5As). This protein activates latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection and diabetes mellitus, type 1. A disease-associated allele in a splice acceptor site influences the production of the p46 splice isoform. This gene is located in a cluster of related genes on chromosome 12. |