Anti-COPS5 Polyclonal Antibody
品牌：solarbio | 货号：K006779P
| 英文名称 | Anti-COPS5 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CSN5;JAB1;SGN5;MOV-34 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:1000-5000. IHC 1:150-500. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 38kDa |
| Gene ID | 10987 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human COPS5 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human COPS5 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q92905 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors |