Anti-TNIP3 Polyclonal Antibody
品牌：solarbio | 货号：K007570P
| 英文名称 | Anti-TNIP3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | LIND;ABIN-3 |
| 应用 | WB |
| 稀释比例 | WB 1:200-1000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 39kDa |
| Gene ID | 79931 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human TNIP3 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human TNIP3 |
| Swiss Prot | Q96KP6 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | TNIP3, which called LIND, that was upregulated in monocytes infected with Listeria monocytogenes. The predicted 325-amino acid protein contains 3 coiled-coil domains and is most likely localized to the nucleus. Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding. |