Anti-KLC1 Polyclonal Antibody
品牌：solarbio | 货号：K004056P
| 英文名称 | Anti-KLC1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | KLC;KNS2;KNS2A |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 65kDa |
| Gene ID | 3831 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human KLC1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human KLC1 |
| Subcellular Locations | Cell projection Cytoplasm Cytoplasmic vesicle cytoskeleton growth cone |
| Swiss Prot | Q07866 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named “kinesin 2”, this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined. |