Anti-RANK Polyclonal Antibody
品牌：solarbio | 货号：K106460P
| 英文名称 | Anti-RANK Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ODFR;CD265;FEO;LOH18CR1;TNFRSF11A |
| 应用 | WB |
| 稀释比例 | WB 1:3000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 56kDa |
| Gene ID | 8792 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human RANK |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human RANK |
| Subcellular Locations | Cell membrane |
| Swiss Prot | Q9Y6Q6 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | CD265 is a member of the tumor necrosis factor receptor (TNFR) family. Human and murine CD265 share 81% amino acid identity in their extracellular domains. CD265 is widely expressed, with highest levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland. CD265 is also expressed in dendritic cells. RANK and RANK ligand (RANKL) are important regulators of interactions between T cells and dendritic cells. RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis. Multiple tumor necrosis factor receptor-associated factors (TRAFs) are involved in the signaling of CD265. |