Anti-SPAG6 Polyclonal Antibody
品牌:solarbio | 货号:K007601P
英文名称 |
Anti-SPAG6 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
pf16;Repro-SA-1 |
应用 |
WB |
稀释比例 |
WB 1:200-1000. |
交叉反应 |
Human Mouse |
蛋白分子量 |
55kDa |
Gene ID |
9576 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human SPAG6 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human SPAG6 |
Swiss Prot |
O75602 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. |