Anti-IL5RA Polyclonal Antibody
品牌：solarbio | 货号：K005909P
| 英文名称 | Anti-IL5RA Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CD125;CDw125;HSIL5R3;IL5R |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 48kDa |
| Gene ID | 3568 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human IL5RA |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human IL5RA |
| Subcellular Locations | Membrane Single-pass type I membrane protein |
| Swiss Prot | Q01344 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. |