Goat Anti-Mouse IgM antibody
| 中文名称 | 羊抗小鼠IgM |
|---|---|
| 别名 | Immunoglobulin M. |
| 应用 | WB=1:1000-5000 ELISA=1:2000-10000 IHC-P=1:200-1000 IHC-F=1:200-1000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 浓度 | 10mg/1ml |
| 蛋白分子量 | 900kDa |
| 保存 | Storage: Store at –20 oC for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20oC. When reconstituted in sterile distilled water or diluent supplied, theantibody is stable for at least two weeks at 2-4 °C. |
| 储存液 | 0.01M PBS(pH7.4) |
| 纯化方法 | affinity purified by Protein A |
| 亚型 | IgG |
| 免疫原 | Full length plasma protein |
| 性状 | Lyophilized or Liquid |
| 克隆类型 | polyclonal |
Background:
Immunoglobulin M (IgM) normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it’s large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it’s high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences.
Also known as: Immunoglobulin M.
Specificity:
●Goat Polyclonal IgG, affinity purified by Protein A.
●Reacts with: mo.
●Immunogen: Full length plasma protein.
●Predicted Molecular Weight: 900kDa.