熊果苷
- 英文名：Arbutin
- 别名：4-羟苯基-β-D-吡喃型葡萄糖苷
- 分子式：C12H16O7
- 分子量：272.25
- CAS：497-76-7
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熊果苷 |
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熊果苷又名熊果素，呈白色针状结晶或粉末。萃取自熊果的叶子，能够通过抑制体内酪氨酸酶的活性，阻止黑色素的生成，从而减少皮肤色素沉积，祛除色斑和雀斑，同时还有杀菌、消炎的作用。主要用于高级化妆品的制备。 |
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Product Name: |
Arbutin |
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Synonyms: |
4-Hydroxyphenyl β-D-Glucopyranoside, Hydroquinone-β-D-glucoside |
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CAS: |
497-76-7 |
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MF: |
C12H16O7 |
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MW: |
272.25 |
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EINECS: |
207-850-3 |
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Arbutin Chemical Properties |
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mp |
195-198 °C |
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alpha |
-64 º (c=3) |
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refractive index |
-65.5 ° (C=4, H2O) |
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storage |
2-8°C |
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solubility |
H2O: 50 mg/mL hot, clear |
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Water Solubility |
10-15 g/100 mL at 20 ºC |
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Sensitive |
Hygroscopic |
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Merck |
14,773 |
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BRN |
89673 |
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Stability: |
Stable. Hygroscopic – store under dry nitrogen. |
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Usage |
Arbutin is a component used in the skin-whitening cosmetics. |
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Safety Information |
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Hazard Codes |
Xn |
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Risk Statements |
20/21/22-36/37/38 |
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Safety Statements |
22-24/25-36-26 |
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WGK Germany |
3 |
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RTECS |
CE8863000 |
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F |
3-1022-24/25-36-26-23 |
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HS Code |
29389090 |
Introduction:
Arbutin is a glycoside; a glycosylated hydroquinone extracted from the bearberry plant in the genus Arctostaphylos; inhibits tyrosinase and thus prevents the formation of melanin. IC50 value: Target: tyrosinase
Function(s): Antioxidant; Skin-Conditioning Agent, Lightening agent
Application
Arbutin, a glycosylated hydroquinone, is used in studies on melanin biosynthesis and as an inhibitor to identify, differentiate and characterize tyrosinase(s).