Anti-UVRAG Polyclonal Antibody
| 英文名称 | Anti-UVRAG Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | DHTX;VPS38;p63 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 78kDa |
| Gene ID | 7405 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human UVRAG |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human UVRAG |
| Subcellular Locations | Chromosome Early endosome Endoplasmic reticulum Late endosome Lysosome Midbody centromere |
| Swiss Prot | Q9P2Y5 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. |