Anti-RNF34 Polyclonal Antibody
| 英文名称 | Anti-RNF34 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CARP-1;CARP1;RFI;RIF;RIFF;hRFI |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human |
| 蛋白分子量 | 42kDa |
| Gene ID | 80196 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human RNF34 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human RNF34 |
| Subcellular Locations | Cell membrane Cytoplasm Endomembrane system Nucleus Nucleus speckle Peripheral membrane protein cytosol |
| Swiss Prot | Q969K3 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms. |