Anti-PMS2 Polyclonal Antibody
| 英文名称 | Anti-PMS2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PMSL2;HNPCC4;PMS2CL |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 96kDa |
| Gene ID | 5395 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human PMS2 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human PMS2 |
| Subcellular Locations | Nucleus |
| Swiss Prot | P54278 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. |