Anti-DTX3L Polyclonal Antibody
品牌：solarbio | 货号：K006729P
| 英文名称 | Anti-DTX3L Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | BBAP |
| 应用 | WB |
| 稀释比例 | WB 1:200-1000. |
| 交叉反应 | Human |
| 蛋白分子量 | 84kDa |
| Gene ID | 151636 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human DTX3L |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human DTX3L |
| Subcellular Locations | Cytoplasm Endosome Lysosome Membrane Nucleus |
| Swiss Prot | Q8TDB6 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The Deltex family is responsible for influencing Notch signaling and may regulate transcription through interactions with specific transcription factors. Deltex proteins have a basic N-terminus, a central proline-rich region and a C-terminal RING-type zinc finger domain, a motif often found in ubiquitin-protein isopeptide ligases (E3). The RING-type zinc finger domain binds two Zn2+ atoms and forms a cross-brace motif that is essential for many proteins involved the ubiquitination pathway. DTX3L (Deltex-3-like), also known as BBAP, is a 740 amino acid protein that is similar to Deltex-3 and acts as a ubiquitin ligase in vitro. DTX3L can heterodimerize with Deltex-1, a transcriptional regulator, thereby enhancing the activity of the E3 ubiquitin ligase complex and increasing the influence of E3 on the Notch signaling pathway. |