Anti-TNNI3 Polyclonal Antibody
品牌：solarbio | 货号：K004924P
| 英文名称 | Anti-TNNI3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CMD1FF;CMD2A;CMH7;RCM1;TNNC1;cTnI |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 24kDa |
| Gene ID | 7137 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human TNNI3 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human TNNI3 |
| Subcellular Locations | Cytoskeleton Cytosol |
| Swiss Prot | P19429 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). |