Anti-PCNA Monoclonal Antibody
品牌：solarbio | 货号：K200030M
| 英文名称 | Anti-PCNA Monoclonal Antibody |
|---|---|
| 宿主 | Mouse |
| 别名 | Proliferating Cell Nuclear Antigen;DNA polymerase delta auxiliary protein;PCNAR |
| 应用 | WB IHC |
| 稀释比例 | WB 1:10000-15000. IHC 1:100-300. |
| 蛋白分子量 | 29kDa |
| Gene ID | 5111 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG1 |
| 免疫原 | A synthetic peptide coupled to KLH |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide coupled to KLH |
| Subcellular Locations | Nucleus |
| Swiss Prot | P12004 |
| 克隆号 | 12D10 |
| 克隆类型 | Monoclonal Antibody |
| 背景资料 | PCNA is a marker for cells in early G1 phase and S phase of the cell cycle. It is found in the nucleus and is a cofactor of DNA polymerase delta. PCNA acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, PCNA is ubiquitinated and is involved in the RAD6 dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for PCNA. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. |