Anti-CASP9 Polyclonal Antibody
品牌：solarbio | 货号：K101548P
| 英文名称 | Anti-CASP9 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | APAF-3;APAF3;ICE-LAP6;MCH6;PPP1R56 |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-200. |
| 交叉反应 | Mouse |
| 蛋白分子量 | 46kDa |
| Gene ID | 842 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human CASP9 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human CASP9 |
| Subcellular Locations | Cytosol Nucleus |
| Swiss Prot | P55211 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9. |