Anti-FOXO1 Polyclonal Antibody
品牌：solarbio | 货号：K007489P
| 英文名称 | Anti-FOXO1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | FKH1;FKHR;FOXO1A |
| 应用 | IHC |
| 稀释比例 | IHC 1:25-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 70kDa |
| Gene ID | 2308 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human FOXO1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human FOXO1 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q12778 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. Interacts with LRPPRC. Interacts with RUNX2; the interaction inhibits RUNX2 transcriptional activity and mediates the IGF1/insulin-dependent BGLAP expression in osteoblasts Interacts with PPP2R1A; the interaction regulates the dephosphorylation of FOXO1 at Thr-24 and Ser-256 leading to its nuclear import. |