Anti-BAK1 Polyclonal Antibody
品牌:solarbio | 货号:K006653P
英文名称 |
Anti-BAK1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
BAK;CDN1;BCL2L7;BAK-LIKE |
应用 |
WB IHC |
稀释比例 |
WB 1:1000-5000. IHC 1:50-200. |
交叉反应 |
Human |
蛋白分子量 |
23kDa |
Gene ID |
578 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human BAK1 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human BAK1 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
Q16611 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. |