Anti-ZFP42 Polyclonal Antibody
品牌：solarbio | 货号：K007656P
| 英文名称 | Anti-ZFP42 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | REX1;ZNF754 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human |
| 蛋白分子量 | 35kDa |
| Gene ID | 132625 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human ZFP42 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human ZFP42 |
| Swiss Prot | Q96MM3 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Rex-1 (for reduced expression), also designated zinc finger protein 42 (ZFP42), is an acidic zinc finger protein. Rex-1 contains four repeats of the zinc finger nucleic acid-binding motif and a potential acidic activator domain, suggesting that it is a regulatory protein. Rex-1 localizes to the nucleus and is highly expressed in embryonic stem (ES) and undifferentiated murine F9 teratocarcinoma cells. At the transcriptional level, expression of Rex-1 is reduced when F9 cells are induced to differentiate by the addition of retinoic acid (RA), and Rex-1 repression is enhanced by E1A. The Oct-3/4 transcription factor can either activate or repress the Rex-1 promoter, depending on the cellular environment, while Oct-6 can lower the expression of Rex-1. |