Anti-CFL1 Polyclonal Antibody
品牌:solarbio | 货号:K106947P
| 英文名称 | Anti-CFL1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | 18 kDa phosphoprotein;CFL;CFL1;Cofilin 1;cofilin 1 (non muscle);Cofilin;non muscle isoform;p18 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:10000-15000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 19kDa |
| Gene ID | 1072 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CFL1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CFL1 |
| Subcellular Locations | All |
| Swiss Prot | P23528 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. |