Anti-TPP1 Polyclonal Antibody
品牌：solarbio | 货号：K004092P
| 英文名称 | Anti-TPP1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CLN2;GIG1;LPIC;SCAR7;TPP-1 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 61kDa |
| Gene ID | 1200 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human TPP1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human TPP1 |
| Subcellular Locations | Lysosome Melanosome |
| Swiss Prot | O14773 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. |