Anti-CASP2 Polyclonal Antibody
品牌:solarbio | 货号:K004163P
| 英文名称 | Anti-CASP2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CASP-2;ICH1;NEDD-2;NEDD2;PPP1R57 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 51kDa |
| Gene ID | 835 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CASP2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CASP2 |
| Subcellular Locations | Cytosol Nucleus Mitochondrion |
| Swiss Prot | P42575 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer’s disease, Huntington’s disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |