Anti-P4HB Polyclonal Antibody
品牌：solarbio | 货号：K106924P
| 英文名称 | Anti-P4HB Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PDI;ERBA2L;PDI;PDIA1;PO4DB |
| 应用 | WB IHC |
| 稀释比例 | WB 1:8000-12000. IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 57kDa |
| Gene ID | 64714 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human P4HB |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human P4HB |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P07237 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis. Also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP. |