Anti-GLDC Polyclonal Antibody
品牌:solarbio | 货号:K006116P
| 英文名称 | Anti-GLDC Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | GCE;GCSP;HYGN1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-500. IHC 1:50-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 113kDa |
| Gene ID | 2731 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human GLDC |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human GLDC |
| Subcellular Locations | Mitochondrion |
| Swiss Prot | P23378 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). |