Anti-CAV3 Polyclonal Antibody
品牌:solarbio | 货号:K005652P
| 英文名称 | Anti-CAV3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | LGMD1C;LQT9;VIP-21;VIP21 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 17kDa |
| Gene ID | 859 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CAV3 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CAV3 |
| Subcellular Locations | Cell membrane Golgi apparatus membrane Membrane Peripheral membrane protein caveola |
| Swiss Prot | P56539 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites. |