Anti-FMOD Polyclonal Antibody
品牌：solarbio | 货号：K004472P
| 英文名称 | Anti-FMOD Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | FM;SLRR2E |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 43kDa |
| Gene ID | 2331 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human FMOD |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human FMOD |
| Subcellular Locations | Secreted extracellular matrix extracellular space |
| Swiss Prot | Q06828 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants. |