Anti-ATG4D Polyclonal Antibody
品牌:solarbio | 货号:K008329P
| 英文名称 | Anti-ATG4D Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | APG4D;AUTL4;APG4-D |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 53/16kDa |
| Gene ID | 84971 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ATG4D |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ATG4D |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q86TL0 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. |