Anti-TNFSF18 Polyclonal Antibody
品牌：solarbio | 货号：K106930P
| 英文名称 | Anti-TNFSF18 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | AITRL;GITRL;TL6;hGITRL |
| 应用 | WB |
| 稀释比例 | WB 1:8000-12000. |
| 交叉反应 | Mouse |
| 蛋白分子量 | 46kDa |
| Gene ID | 8995 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human TNFSF18 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human TNFSF18 |
| Subcellular Locations | Cell membrane? |
| Swiss Prot | Q9UNG2 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1. Promotes leukocyte adhesion to endothelial cells. Regulates migration of monocytes from the splenic reservoir to sites of inflammation (By similarity). |