Anti-TNFSF12 Polyclonal Antibody
品牌：solarbio | 货号：K004114P
| 英文名称 | Anti-TNFSF12 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | APO3L;DR3LG;TNLG4A;TWEAK |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 27kDa |
| Gene ID | 8742 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human TNFSF12 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human TNFSF12 |
| Subcellular Locations | Cell membrane Secreted Single-pass membrane protein Single-pass type II membrane protein |
| Swiss Prot | O43508 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. |