Anti-WHSC1 Polyclonal Antibody
品牌：solarbio | 货号：K007976P
| 英文名称 | Anti-WHSC1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | WHS;NSD2;TRX5;MMSET;REIIBP |
| 应用 | IHC |
| 稀释比例 | IHC 1:25-100. |
| 交叉反应 | Human |
| 蛋白分子量 | 152/81/69/53/30kDa |
| Gene ID | 7468 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human WHSC1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human WHSC1 |
| Subcellular Locations | Nucleus |
| Swiss Prot | O96028 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences. |