Anti-RNF8 Polyclonal Antibody
品牌：solarbio | 货号：K005155P
| 英文名称 | Anti-RNF8 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | hRNF8 |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 56kDa |
| Gene ID | 9025 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human RNF8 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human RNF8 |
| Subcellular Locations | Chromosome Midbody Nucleus telomere |
| Swiss Prot | O76064 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants. |