Anti-PRAME Polyclonal Antibody
品牌:solarbio | 货号:K004543P
| 英文名称 | Anti-PRAME Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CT130;MAPE;OIP-4;OIP4 |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:20-50. |
| 交叉反应 | Human |
| 蛋白分子量 | 58kDa |
| Gene ID | 23532 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PRAME |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PRAME |
| Subcellular Locations | Cell membrane Nucleus |
| Swiss Prot | P78395 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues except testis. The encoded protein acts as a repressor of retinoic acid receptor and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. |