Anti-COX7A2L Polyclonal Antibody
品牌：solarbio | 货号：K008131P
| 英文名称 | Anti-COX7A2L Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | EB1;SIG81;COX7AR;COX7RP |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:30-150. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 13kDa |
| Gene ID | 9167 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Full length Recombinant protein |
| 性状 | 液体 |
| Public Immunogen Range | Full length Recombinant protein |
| Subcellular Locations | Mitochondrion inner Membrane |
| Swiss Prot | O14548 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene. |