Anti-COX11 Polyclonal Antibody
品牌：solarbio | 货号：K008132P
| 英文名称 | Anti-COX11 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | COX11P |
| 应用 | WB IHC |
| 稀释比例 | WB 1:1000-5000. IHC 1:25-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 31kDa |
| Gene ID | 1353 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human COX11 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human COX11 |
| Subcellular Locations | Cytoplasm Membrane |
| Swiss Prot | Q9Y6N1 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies. However, the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu(B) and magnesium centers of COX. This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene has been found on chromosome 6.? |