Anti-TIMM8A Polyclonal Antibody
品牌：solarbio | 货号：K007330P
| 英文名称 | Anti-TIMM8A Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | DDP;MTS;DDP1;DFN1;TIM8 |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-300. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 11kDa |
| Gene ID | 1678 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human TIMM8A |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human TIMM8A |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | O60220 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome; an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |