Anti-SAP18 Polyclonal Antibody
品牌:solarbio | 货号:K003792P
| 英文名称 | Anti-SAP18 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | 2HOR0202;SAP18P |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 18kDa |
| Gene ID | 10284 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human SAP18 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human SAP18 |
| Subcellular Locations | Cytoplasm Nucleus Nucleus speckle |
| Swiss Prot | O00422 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2. |