Anti-ADD1 Polyclonal Antibody
品牌：solarbio | 货号：K006638P
| 英文名称 | Anti-ADD1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ADDA |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 81kDa |
| Gene ID | 118 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ADD1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ADD1 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P35611 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described. |