Anti-EIF4G2 Polyclonal Antibody
品牌:solarbio | 货号:K007419P
英文名称 |
Anti-EIF4G2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
P97;AAG1;DAP5;NAT1 |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse |
蛋白分子量 |
103kDa |
Gene ID |
1982 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human EIF4G2 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human EIF4G2 |
Subcellular Locations |
Cytosol |
Swiss Prot |
P78344 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. |