Anti-CRK Polyclonal Antibody
品牌：solarbio | 货号：K007000P
| 英文名称 | Anti-CRK Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | p38;CRKII |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 34kDa |
| Gene ID | 1398 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CRK |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CRK |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P46108 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. |