Anti-ICAM1 Polyclonal Antibody
品牌：solarbio | 货号：K008365P
| 英文名称 | Anti-ICAM1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | BB2;CD54;P3.58 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:1000-5000. IHC 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 58kDa |
| Gene ID | 3383 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ICAM1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ICAM1 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P05362 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. |